iSAN Bio 株式会社

Japan is developing an aging society at rapid pace, the key for creating a free and tolerant society is to enable the adult generation to design and adjust their lives more flexibly. Alzheimer’s disease (dementia), which often develops with the aging of the population, is a medical and social issue not only in Japan but worldwide. As we saw that early diagnosis and treatment of cancer lead to cure, we believe that early diagnosis of Alzheimer’s disease is also critical for greater efficacy or delay of the onset with therapeutic drugs. In addition, developing technologies that can detect Alzheimer’s disease at an early or pre-disease stage would not only help in its treatment but also provide concrete decisions about future concerns. Through the development of technologies, mainly early diagnosis methods for Alzheimer’s disease, we hope to contribute for better welfare planning and everyone’s happiness

Our Technology for Early Diagnosis of Alzheimer’s Disease

Alzheimer’s disease is the leading cause of dementia, accounting for approximately 68% of all cases in Japan. The accumulation of amyloid-β in the brain is involved in the pathogenesis of Alzheimer’s disease. The accumulated amyloid-β causes abnormal phosphorylation of tau protein and the formation of neurofibrillary tangles. These accumulations and changes cause neuronal damage, resulting in the destruction of neurons and the onset of dementia

For more information